Inhibition of p53 DNA binding by human papillomavirus E6 proteins.

Transformation by the human papillomavirus (HPV) early gene products, E6 and E7, involves their interaction with cellular proteins p53 and Rb. Using glutathione S-transferase (GST) fusion proteins, we found that HPV E6 bound human p53 and that the relative efficiency of binding varied such that the...

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Bibliographic Details
Published in:J Virol
Main Authors: Lechner, M S, Laimins, L A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236349/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8207801/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.7.4262-4273.1994
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