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AQ4N: a new approach to hypoxia-activated cancer chemotherapy

Preclinical studies demonstrate that in vivo AQ4N enhances the anti-tumour effects of radiation and chemotherapeutic agents with a dose-modifying factor of approximately 2.0. With careful scheduling no, or very little, additional normal tissue toxicity should be observed. AQ4N is a bioreductive prod...

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Autori principali: Patterson, L H, McKeown, S R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363465/
https://ncbi.nlm.nih.gov/pubmed/11104551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1564
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