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Population carrier frequency of hMSH2 and hMLH1 mutations

Knowledge of population carrier frequency for DNA mismatch repair (MMR) gene mutations would contribute to understanding the burden of cancer due to genetic susceptibility, but robust prevalence estimates are lacking. To estimate carrier frequency, we genotyped a cohort of relatives of mutation carr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dunlop, M G, Farrington, S M, Nicholl, I, Aaltonen, L, Petersen, G, Porteous, M, Carothers, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363440/
https://ncbi.nlm.nih.gov/pubmed/11104559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1520
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