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The constitutive level of vascular endothelial growth factor (VEGF) is more important than hypoxia-induced VEGF up-regulation in the angiogenesis of human melanoma xenografts

Angiogenesis of tumours might develop as a result of environmental conditions, such as hypoxia, and/or as a result of genetic alterations specific for tumour cells. The relative contributions of these mechanisms were investigated by comparing the in vivo expression of vascular endothelial growth fac...

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Autori principali: Danielsen, T, Rofstad, E K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363386/
https://ncbi.nlm.nih.gov/pubmed/10789719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1173
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