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A dominant negative mutation of transforming growth factor- β receptor type II gene in microsatellite stable oesophageal carcinoma
Recent investigations revealed microsatellite instability in colon cancers are associated with mutations of the transforming growth factor-β receptor type II gene (TGF-β RII) that encodes a transmembrane protein containing an intracellular serine/threonine kinase domain. Activation of TGF-β receptor...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363384/ https://ncbi.nlm.nih.gov/pubmed/10789724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1178 |
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