A dominant negative mutation of transforming growth factor- β receptor type II gene in microsatellite stable oesophageal carcinoma

Recent investigations revealed microsatellite instability in colon cancers are associated with mutations of the transforming growth factor-β receptor type II gene (TGF-β RII) that encodes a transmembrane protein containing an intracellular serine/threonine kinase domain. Activation of TGF-β receptor...

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Bibliografske podrobnosti
Main Authors: Tanaka, Shinji, Mori, Masaki, Mafune, Ken–ichi, Ohno, Shinji, Sugimachi, Keizo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2000
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363384/
https://ncbi.nlm.nih.gov/pubmed/10789724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1178
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