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Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer
A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its presence does not apparently affect hMSH2 function. © 2000 Cancer Research Campaign
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363304/ https://ncbi.nlm.nih.gov/pubmed/10682661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0959 |
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