Anti-tumour activity of tachykinin NK(1)receptor antagonists on human glioma U373 MG xenograft

Astrocytes harbour functional receptors to many neurotransmitters, including substance P (SP), an undecapeptide belonging to the tachykinin family of peptide transmitters. SP activates malignant glial cells to induce cytokine release and proliferation, both responses being relevant for tumour progre...

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Bibliographic Details
Main Authors: Palma, C, Bigioni, M, Irrissuto, C, Nardelli, F, Maggi, C A, Manzini, S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2000
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363296/
https://ncbi.nlm.nih.gov/pubmed/10646908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0946
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