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Anti-tumour activity of tachykinin NK(1)receptor antagonists on human glioma U373 MG xenograft
Astrocytes harbour functional receptors to many neurotransmitters, including substance P (SP), an undecapeptide belonging to the tachykinin family of peptide transmitters. SP activates malignant glial cells to induce cytokine release and proliferation, both responses being relevant for tumour progre...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363296/ https://ncbi.nlm.nih.gov/pubmed/10646908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0946 |
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