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BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma

The expression of the BCL-2 family proteins, BCL-2, BAX, BCL(XL)and BAK have been determined in a panel of 12 human ovarian carcinoma cell lines encompassing a wide range in sensitivity to cisplatin. Whereas BAX, BCL(XL)and BAK levels did not correlate with sensitivity, there was a statistically sig...

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Detalhes bibliográficos
Main Authors: Beale, P J, Rogers, P, Boxall, F, Sharp, S Y, Kelland, L R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363292/
https://ncbi.nlm.nih.gov/pubmed/10646901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0939
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