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Novel therapeutic approach: organic arsenical (melarsoprol) alone or with all-trans -retinoic acid markedly inhibit growth of human breast and prostate cancer cells in vitro and in vivo

The organic arsenical known as melarsoprol (Mel-B) is used to treat African trypanosomiasis. Recently, another arsenical, As(2)O(3)was shown to be effective in treatment of acute promyelocytic leukaemia. We have investigated the anti-tumour activities of Mel-B either with or without all-trans -retin...

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Main Authors: Koshiuka, K, Elstner, E, Williamson, E, Said, J W, Tada, Y, Koeffler, H P
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363281/
https://ncbi.nlm.nih.gov/pubmed/10646904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0942
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