Failure in post-transcriptional processing is a possible inactivation mechanism of AP-2 α in cutaneous melanoma

The loss of transcription factor AP-2α expression has been shown to associate with tumourigenicity of melanoma cell lines and poor prognosis in primary cutaneous melanoma. Altogether these findings suggest that the gene encoding AP-2α (TFAP2A) acts as a tumour suppressor in melanoma. To learn more o...

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Detalles Bibliográficos
Autores principales: Karjalainen, J M, Kellokoski, J K, Mannermaa, A J, Kujala, H E, Moisio, K I, Mitchell, P J, Eskelinen, M J, Alhava, E M, Kosma, V M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363258/
https://ncbi.nlm.nih.gov/pubmed/10864211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1145
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