Failure in post-transcriptional processing is a possible inactivation mechanism of AP-2 α in cutaneous melanoma

The loss of transcription factor AP-2α expression has been shown to associate with tumourigenicity of melanoma cell lines and poor prognosis in primary cutaneous melanoma. Altogether these findings suggest that the gene encoding AP-2α (TFAP2A) acts as a tumour suppressor in melanoma. To learn more o...

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Bibliographic Details
Main Authors: Karjalainen, J M, Kellokoski, J K, Mannermaa, A J, Kujala, H E, Moisio, K I, Mitchell, P J, Eskelinen, M J, Alhava, E M, Kosma, V M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2000
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363258/
https://ncbi.nlm.nih.gov/pubmed/10864211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1145
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