A dose-finding study of raltitrexed (tomudex) with cisplatin and epirubicin in advanced gastro-oesophageal adenocarcinoma

The standard treatment for advanced gastro-oesophageal cancer in the UK is epirubicin, cisplatin and continuous infusion 5-fluoruracil by an indwelling central venous catheter (ECF), which has significant morbidity. Raltitrexed (tomudex), a specific inhibitor of thymidylate synthase with a long plas...

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Dettagli Bibliografici
Autori principali: Eatock, M M, Anthony, D A, El-Abassi, M, Wilson, P, Paul, J, Smith, M, Soukop, M, Evans, T R J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2000
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363246/
https://ncbi.nlm.nih.gov/pubmed/10864199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1165
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