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Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss

Neuroblastoma (NB) is a well-known malignant disease in infants, but its molecular mechanisms have not yet been fully elucidated. To investigate the genetic contribution of abnormalities on the long arm of chromosome 14 (14q) in NB, we analysed loss of heterozygosity (LOH) in 54 primary NB samples u...

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Hlavní autoři: Hoshi, M, Otagiri, N, Shiwaku, H O, Asakawa, S, Shimizu, N, Kaneko, Y, Ohi, R, Hayashi, Y, Horii, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363232/
https://ncbi.nlm.nih.gov/pubmed/10839294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1108
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