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KRAS Alleles: The Devil Is In The Detail
KRAS is the most frequently mutated oncogene in cancer and KRAS mutation is commonly associated with poor prognosis and resistance to therapy. Since the KRAS oncoprotein is, as yet, not directly druggable, efforts to target KRAS mutant cancers focus on identifying vulnerabilities in downstream signa...
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| Wydane w: | Trends Cancer |
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| 1. autor: | |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824632/ https://ncbi.nlm.nih.gov/pubmed/28958387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.08.006 |
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