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Histamine, mast cells and tumour cell proliferation in breast cancer: does preoperative cimetidine administration have an effect?

Endogenous histamine has been shown to effect growth mechanisms in experimental mammary carcinomas via H2 membrane receptors (Cricco et al, 1994). Both H1 and H2 binding sites are present in human mammary glands but only 75% malignant carcinomas express H2 receptors (Lemos et al, 1995). The presence...

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Bibliografische gegevens
Hoofdauteurs: Bowrey, P F, King, J, Magarey, C, Schwartz, P, Marr, P, Bolton, E, Morris, D L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363200/
https://ncbi.nlm.nih.gov/pubmed/10638985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0895
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