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Histamine, mast cells and tumour cell proliferation in breast cancer: does preoperative cimetidine administration have an effect?

Endogenous histamine has been shown to effect growth mechanisms in experimental mammary carcinomas via H2 membrane receptors (Cricco et al, 1994). Both H1 and H2 binding sites are present in human mammary glands but only 75% malignant carcinomas express H2 receptors (Lemos et al, 1995). The presence...

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Detalhes bibliográficos
Main Authors: Bowrey, P F, King, J, Magarey, C, Schwartz, P, Marr, P, Bolton, E, Morris, D L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363200/
https://ncbi.nlm.nih.gov/pubmed/10638985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0895
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