Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model

The Auger electron emitting agent 5-[(125)I]iodo-2′-deoxyuridine (i.e.[(125)I]IUdR) holds promise for the treatment of residual glioma after surgery because this thymidine analogue kills only proliferating cells. However, malignant cells which are not synthesizing DNA during exposure to the radiopha...

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Detalhes bibliográficos
Main Authors: Mairs, R J, Wideman, C L, Angerson, W J, Whateley, T L, Reza, M S, Reeves, J R, Robertson, L M, Neshasteh-Riz, A, Rampling, R, Owens, J, Allan, D, Graham, D I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363176/
https://ncbi.nlm.nih.gov/pubmed/10638969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0879
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