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Ribozyme inhibition of the protein kinase Cα triggers apoptosis in glioma cells

Although protein kinase C has been shown to be involved in a wide range of biological functions, the precise role of each isoform in a specific cell function remains to be clarified. Here we demonstrate that a ribozyme specific for the human protein kinase Cα (PKCα), a classical PKC isoform, induces...

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Detalhes bibliográficos
Main Authors: Leirdal, M, Sioud, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363167/
https://ncbi.nlm.nih.gov/pubmed/10408397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690560
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