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Acidic environment causes apoptosis by increasing caspase activity
An exposure of HL-60 human promyelocytic leukaemia cells to acidic media with pH 6.2–6.6 caused an up-regulation of Bax protein expression within 2 h, which lasted for longer than 6 h. On the other hand, the apoptosis, as judged from PARP cleavage, DNA fragmentation and flow cytometric determination...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363148/ https://ncbi.nlm.nih.gov/pubmed/10471036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690617 |
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