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Mathematical and experimental analysis of localization of anti-tumour antibody–enzyme conjugates
Considerable research has been aimed at improving the efficacy of chemotherapeutic agents for cancer therapy. A promising two-step approach that is designed to minimize systemic drug toxicity while maximizing activity in tumours employs monoclonal antibody (mAb)–enzyme conjugates for the activation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363130/ https://ncbi.nlm.nih.gov/pubmed/10468291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690592 |
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