Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis

Colonic enterocytes, like many epithelial cells in vivo, are polarized with functionally distinct apical and basolateral membrane domains. The aims of this study were to characterize the endogenous epidermal growth factor (EGF)-like ligands expressed in two polarizing colon cancer cell lines, HCA-7...

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Autori principali: Damstrup, L, Kuwada, S K, Dempsey, P J, Brown, C L, Hawkey, C J, Poulsen, H S, Wiley, H S, Coffey, R J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1999
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363033/
https://ncbi.nlm.nih.gov/pubmed/10362109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690456
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