Altered expression of the suppressors PML and p53 in glioblastoma cells with the antisense-EGF-receptor

Gene amplification and enhanced expression of the epidermal growth factor receptor (EGFR) represent the major molecular genetic alteration in glioblastomas and it may play an essential role in cell growth and in the carcinogenic process. On the other hand, the nuclear suppressor proteins PML and p53...

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Detalhes bibliográficos
Main Authors: Tian, X X, Chan, J Y H, Pang, J C S, Chen, J, He, J H, To, T S S, Leung, S F, Ng, H K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362944/
https://ncbi.nlm.nih.gov/pubmed/10576656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690798
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