Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug

Triabin, a 142-residue protein from the saliva of the blood-sucking triatomine bug Triatoma pallidipennis, is a potent and selective thrombin inhibitor. Its stoichiometric complex with bovine α-thrombin was crystallized, and its crystal structure was solved by Patterson search methods and refined at...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Fuentes-Prior, Pablo, Noeske-Jungblut, Christiane, Donner, Peter, Schleuning, Wolf-Dieter, Huber, Robert, Bode, Wolfram
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9342325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.22.11845
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