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Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug

Triabin, a 142-residue protein from the saliva of the blood-sucking triatomine bug Triatoma pallidipennis, is a potent and selective thrombin inhibitor. Its stoichiometric complex with bovine α-thrombin was crystallized, and its crystal structure was solved by Patterson search methods and refined at...

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Detalhes bibliográficos
Main Authors: Fuentes-Prior, Pablo, Noeske-Jungblut, Christiane, Donner, Peter, Schleuning, Wolf-Dieter, Huber, Robert, Bode, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23629/
https://ncbi.nlm.nih.gov/pubmed/9342325
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