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The distinct role of CD4(+) and CD8(+) T-cells during the anti-tumour effects of targeted superantigens
To target T-cells to the tumour area we created a recombinant protein of the bacterial superantigen (SAg) Staphylococcal enterotoxin A (SEA) and the Fab-fragment of a tumour-reactive antibody. This antibody-targeted SAg immunotherapy therapy has been shown to be highly efficient, eliminating > 95...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362868/ https://ncbi.nlm.nih.gov/pubmed/10496366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690701 |
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