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Low frequency of germline E-cadherin mutations in familial and nonfamilial gastric cancer

Little is known about the relative contributions of genetic and environmental factors to the development of gastric cancer. Mutations in the cell adhesion molecule E-cadherin are recognized to be associated with the development of undifferentiated, diffuse and invasive gastric cancers. A recent stud...

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Autori principali: Stone, J, Bevan, S, Cunningham, D, Hill, A, Rahman, N, Peto, J, Marossy, A, Houlston, R S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362779/
https://ncbi.nlm.nih.gov/pubmed/10206317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690308
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