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The promoter and the enhancer region of the KLK 3 (prostate specific antigen) gene is frequently mutated in breast tumours and in breast carcinoma cell lines

KLK3 or prostate specific antigen (PSA) is a serine protease, which is an established tumour marker of prostatic adenocarcinoma. PSA is now used widely for the diagnosis and monitoring of patients with prostate cancer. Recent studies have demonstrated that about 70% of breast cancers produce PSA. In...

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Detalhes bibliográficos
Main Authors: Majumdar, S, Diamandis, E P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362704/
https://ncbi.nlm.nih.gov/pubmed/10188912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690254
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