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Droplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations

BACKGROUND: Breast fibroadenoma (FA) and phyllodes tumour (PT) often have variations of gene mediator complex subunit 12 (MED12) and mutations in the telomerase reverse transcriptase promoter region (TERTp). TERTp mutation is usually tested by Sanger sequencing. In this study, we compared Sanger seq...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Cancer
Hauptverfasser: Otsuji, Kazutaka, Sasaki, Takeshi, Tanabe, Masahiko, Seto, Yasuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852881/
https://ncbi.nlm.nih.gov/pubmed/33046803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01109-8
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