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Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations

High-dose busulphan-containing chemotherapy regimens have shown high response rates in children with relapsed or refractory neuroblastoma, Ewing's sarcoma and medulloblastoma. However, the anti-tumour activity of busulfan as a single agent remains to be defined, and this was evaluated in athymi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Boland, I, Vassal, G, Morizet, J, Terrier-Lacombe, M-J, Valteau-Couanet, D, Kalifa, C, Hartmann, O, Gouyette, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362679/
https://ncbi.nlm.nih.gov/pubmed/10070870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690126
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