Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas

PTEN is a novel tumour-suppressor gene located on chromosomal band 10q23.3. This region displays frequent loss of heterozygosity (LOH) in a variety of human neoplasms including breast carcinomas. The detection of PTEN mutations in Cowden disease and in breast carcinoma cell lines suggests that PTEN...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Freihoff, D, Kempe, A, Beste, B, Wappenschmidt, B, Kreyer, E, Hayashi, Y, Meindl, A, Krebs, D, Wiestler, O D, Deimling, A von, Schmutzler, R K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1999
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362671/
https://ncbi.nlm.nih.gov/pubmed/10070865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690121
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