Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas

PTEN is a novel tumour-suppressor gene located on chromosomal band 10q23.3. This region displays frequent loss of heterozygosity (LOH) in a variety of human neoplasms including breast carcinomas. The detection of PTEN mutations in Cowden disease and in breast carcinoma cell lines suggests that PTEN...

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Detalhes bibliográficos
Main Authors: Freihoff, D, Kempe, A, Beste, B, Wappenschmidt, B, Kreyer, E, Hayashi, Y, Meindl, A, Krebs, D, Wiestler, O D, Deimling, A von, Schmutzler, R K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362671/
https://ncbi.nlm.nih.gov/pubmed/10070865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690121
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