Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc

Apoptosis plays a major role in gastrointestinal epithelial cell turnover, ulcerogenesis and tumorigenesis. We have examined apoptosis induction by non-steroidal anti-inflammatory drugs (NSAIDs) in human gastric (AGS) cancer cells and the role of protein kinase C (PKC) and apoptosis-related oncogene...

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Hlavní autoři: Zhu, G H, Wong, B C Y, Eggo, M C, Ching, C K, Yuen, S T, Chan, E Y T, Lai, K C, Lam, S K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1999
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362449/
https://ncbi.nlm.nih.gov/pubmed/10027304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690062
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