Marimastat in recurrent colorectal cancer: exploratory evaluation of biological activity by measurement of carcinoembryonic antigen

Marimastat is a specific inhibitor of matrix metalloproteinases that has been shown to be effective in cancer models. A pilot, escalating-dose study of oral marimastat was performed in patients with recurrent colorectal cancer, in whom evaluation of serological response was made by measurement of ca...

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Main Authors: Primrose, J N, Bleiberg, H, Daniel, F, Belle, S Van, Mansi, J L, Seymour, M, Johnson, P W, Neoptolemos, J P, Baillet, M, Barker, K, Berrington, A, Brown, P D, Millar, A W, Lynch, K P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1999
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362442/
https://ncbi.nlm.nih.gov/pubmed/10027321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690079
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