Results of single and repeat dose studies of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteers

AIMS: To assess the tolerability and pharmacokinetic profile of single and repeat doses of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteers. METHODS: A total of 31 subjects participated in two placebo-controlled, rising-dose studies. The first study assessed the phar...

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Detalhes bibliográficos
Main Authors: Millar, Andrew W, Brown, Peter D, Moore, Jeff, Galloway, W Alan, Cornish, Alan G, Lenehan, Terence J, Lynch, Kevin P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873993/
https://ncbi.nlm.nih.gov/pubmed/9489589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00639.x
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