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Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas

Expression of CDX2, a caudal-related homeobox gene, was found to be decreased in colorectal carcinomas. Heterozygous null mutant mice as to Cdx2 develop multiple intestinal adenomatous polyps. To clarify the role of CDX2 in colorectal carcinogenesis, we determined its genomic structure, and searched...

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Hlavní autoři: Yagi, O K, Akiyama, Y, Yuasa, Y
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362430/
https://ncbi.nlm.nih.gov/pubmed/10027310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690068
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