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Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas

Expression of CDX2, a caudal-related homeobox gene, was found to be decreased in colorectal carcinomas. Heterozygous null mutant mice as to Cdx2 develop multiple intestinal adenomatous polyps. To clarify the role of CDX2 in colorectal carcinogenesis, we determined its genomic structure, and searched...

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Detalhes bibliográficos
Main Authors: Yagi, O K, Akiyama, Y, Yuasa, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362430/
https://ncbi.nlm.nih.gov/pubmed/10027310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690068
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