Alteration of p16 and p15 genes in human uterine tumours

The roles of the p16 and p15 inhibitor of cyclin-dependent kinase tumour suppressor genes were examined in human uterine cervical and endometrial cancers. p16 mRNA, examined by reverse transcription polymerase chain reaction (RT-PCR), was significantly reduced in five of 19 (26%) cervical and four o...

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Main Authors: Nakashima, R, Fujita, M, Enomoto, T, Haba, T, Yoshino, K, Wada, H, Kurachi, H, Sasaki, M, Wakasa, K, Inoue, M, Buzard, G, Murata, Y
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1999
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362344/
https://ncbi.nlm.nih.gov/pubmed/10408854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690379
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