Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas

Since proteolysis of the dermal collagenous matrix and basement membranes is required for local invasive growth and early metastasis formation of cutaneous melanomas, we have analysed the activities/expression levels of certain metalloproteinases in melanomas and cultured melanoma cells by in situ h...

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Hlavní autoři: Airola, K, Karonen, T, Vaalamo, M, Lehti, K, Lohi, J, Kariniemi, A-L, Keski-Oja, J, Saarialho-Kere, U K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1999
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362286/
https://ncbi.nlm.nih.gov/pubmed/10360651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690417
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