A modified Trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer

The immunohistochemical determination of HER-2 to identify patients with advanced breast cancer candidates for Trastuzumab treatment proved neither accurate nor fully reliable, possibly because none of the current reagents detects the specific antigenic site target of Trastuzumab. To circumvent this...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bussolati, G, Montemurro, F, Righi, L, Donadio, M, Aglietta, M, Sapino, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2005
Pynciau:
Molecular Diagnostics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361978/
https://ncbi.nlm.nih.gov/pubmed/15812476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602507
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