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A modified Trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer

The immunohistochemical determination of HER-2 to identify patients with advanced breast cancer candidates for Trastuzumab treatment proved neither accurate nor fully reliable, possibly because none of the current reagents detects the specific antigenic site target of Trastuzumab. To circumvent this...

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Detalhes bibliográficos
Main Authors: Bussolati, G, Montemurro, F, Righi, L, Donadio, M, Aglietta, M, Sapino, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361978/
https://ncbi.nlm.nih.gov/pubmed/15812476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602507
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