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Mutation screening and association study of RNASEL as a prostate cancer susceptibility gene

To date, germline mutations have been found in three candidate genes for hereditary prostate cancer: ELAC2 at 17p11, RNASEL at 1q25 and MSR1 at 8p22. RNASEL, encoding the 2′,5′-oligoadenylate-dependant RNase L, seems to have rare mutations in different ethnicities, such as M1I in Afro-Americans, E26...

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Détails bibliographiques
Auteurs principaux: Maier, C, Haeusler, J, Herkommer, K, Vesovic, Z, Hoegel, J, Vogel, W, Paiss, T
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361943/
https://ncbi.nlm.nih.gov/pubmed/15714208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602401
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