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Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions

Interleukin-4 (IL-4) is an immunomodulatory cytokine, which can inhibit the growth of tumour cells. Pancreatic cancer cells and tissues express high levels of IL-4 receptors. The aim of this study was to characterise the effects of IL-4 on the growth and signalling pathways of pancreatic cancer cell...

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Bibliografiske detaljer
Main Authors: Prokopchuk, O, Liu, Y, Henne-Bruns, D, Kornmann, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361902/
https://ncbi.nlm.nih.gov/pubmed/15714203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602416
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