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Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects
Dendritic and lymphoid ‘exosomes’ regulate immune activation. Tumours release membranous material mimicking these ‘exosomes,’ resulting in deletion of reactive lymphocytes. Tumour-derived ‘exosomes’ have recently been explored as vaccines, without analysis of their immunologic consequences. This inv...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361848/ https://ncbi.nlm.nih.gov/pubmed/15655551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602316 |
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