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Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects

Dendritic and lymphoid ‘exosomes’ regulate immune activation. Tumours release membranous material mimicking these ‘exosomes,’ resulting in deletion of reactive lymphocytes. Tumour-derived ‘exosomes’ have recently been explored as vaccines, without analysis of their immunologic consequences. This inv...

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מידע ביבליוגרפי
Main Authors: Taylor, D D, Gerçel-Taylor, C
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361848/
https://ncbi.nlm.nih.gov/pubmed/15655551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602316
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