Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma

Suramin is an antitrypanosomal agent with antineoplastic activity, but with serious systemic side effects. We administered Suramin intravesically to determine a concentration with low toxicity but with evidence of a pharmacodynamic effect, to recommend a dose level for phase II trials. This was an o...

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Bibliografiske detaljer
Main Authors: Ord, J J, Streeter, E, Jones, A, Le Monnier, K, Cranston, D, Crew, J, Joel, S P, Rogers, M A, Banks, R E, Roberts, I S D, Harris, A L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361814/
https://ncbi.nlm.nih.gov/pubmed/15928663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602650
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