Pooled peptides from HER-2/neu-overexpressing primary ovarian tumours induce CTL with potent antitumour responses in vitro and in vivo

Unfractionated peptides (MW: up to 10 kDa), derived from HLA-A2.1 positive (+) HER-2/neu-overexpressing primary tumour cell acid cell extracts (ACE), were successfully used to generate in vitro cytotoxic T lymphocytes (CTL). Primary tumour cells were collected from peritoneal malignant effusions of...

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Bibliografiske detaljer
Main Authors: Gritzapis, A D, Perez, S A, Baxevanis, C N, Papamichail, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361747/
https://ncbi.nlm.nih.gov/pubmed/15583693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602259
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