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Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer
The Fanconi gene family has a role in DNA repair and inactivation of FANCF has been proposed as a mechanism of sensitisation to platinum chemotherapy. This study sought to confirm this hypothesis in cell lines and a large series of ovarian cancer samples. Promoter methylation was assessed by methyla...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361708/ https://ncbi.nlm.nih.gov/pubmed/18414472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604325 |
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