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Endostatin expression in a pancreatic cell line is modulated by a TNFα-dependent elastase

Endostatin, an inhibitor of angiogenesis, is a 20 kDa fragment of the basement membrane protein, collagen XVIII. The formation of endostatin relies upon the action of proteases on collagen XVIII. TNFα, produced by activated macrophages, is a multifunctional proinflammatory cytokine with known effect...

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書目詳細資料
Main Authors: Brammer, R D, Bramhall, S R, Eggo, M C
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361670/
https://ncbi.nlm.nih.gov/pubmed/16234817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602835
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