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Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines

Manganese superoxide dismutase (SOD2) is an enzyme that catalyses the dismutation of superoxide in the mitochondria, leading to reduced levels of reactive oxygen species. Reduced expression levels of SOD2 have been shown to result in increased DNA damage and sod2 heterozygous mice have increased inc...

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Detalhes bibliográficos
Main Authors: Hurt, E M, Thomas, S B, Peng, B, Farrar, W L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360443/
https://ncbi.nlm.nih.gov/pubmed/17895890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604000
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