hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells

Telomerase activity is suppressed in normal somatic tissues but is activated in most cancer cells. We have previously found that all six telomerase subunit proteins, including hTERT and hsp90 are needed for full enzyme activity. Telomerase activity has been reported to be upregulated by protein kina...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chang, J T, Lu, Y-C, Chen, Y-J, Tseng, C-P, Chen, Y-L, Fang, C-W, Cheng, A-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361368/
https://ncbi.nlm.nih.gov/pubmed/16508638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados